Future directions for medicinal chemistry in the field of oligonucleotide therapeutics
Abstract
In the last decade, the field of oligonucleotide therapeutics has matured, with the regulatory approval of several single stranded and double stranded RNA drugs. In this perspective, I discuss enabling developments and likely future directions in the field from the perspective of oligonucleotide chemistry.
- Received November 9, 2022.
- Accepted January 9, 2023.
- Published by Cold Spring Harbor Laboratory Press for the RNA Society
This article, published in RNA, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.
