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We show that identification is possible based on the observation sequences of some essential torsion or backbone angles. In particular, the method still provides good results even if the conformations do have a strong overlap in these angles. To apply HMMs to angular data, we use von Mises output distributions. The performance of the resulting method is illustrated by numerical tests and by application to a hybrid Monte Carlo time series of trialanine and to MD simulation results of a DNA\u2013oligomer.<\/jats:p>","DOI":"10.1002\/jcc.20692","type":"journal-article","created":{"date-parts":[[2007,8,6]],"date-time":"2007-08-06T13:16:21Z","timestamp":1186406181000},"page":"2453-2464","source":"Crossref","is-referenced-by-count":13,"title":["Identification of biomolecular conformations from incomplete torsion angle observations by hidden markov models"],"prefix":"10.1002","volume":"28","author":[{"given":"Alexander","family":"Fischer","sequence":"first","affiliation":[]},{"given":"Sonja","family":"Waldhausen","sequence":"additional","affiliation":[]},{"given":"Illia","family":"Horenko","sequence":"additional","affiliation":[]},{"given":"Eike","family":"Meerbach","sequence":"additional","affiliation":[]},{"given":"Christof","family":"Sch\u00fctte","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2007,8,6]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.3798113"},{"key":"e_1_2_7_3_2","first-page":"145","volume":"29","author":"Frauenfelder H.","year":"1989","journal-title":"Chem Soc"},{"key":"e_1_2_7_4_2","series-title":"Handbook of Numerical Analysis","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/S1570-8659(03)10013-0","author":"Sch\u00fctte C.","year":"2003"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1006\/jcph.1999.6231"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.7.2902"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/prot.340170408"},{"key":"e_1_2_7_8_2","first-page":"267","volume-title":"A Tutorial on Hidden Markov Models and Selected Applications in Speech Recognition","author":"Rabiner L. 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