@at_ray_o
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Now a team of researchers from The University of Texas at Austin has built the first theoretical model of condensin to explore cell "packing."
Loop extrusion paper
Loop extrusion paper
How chromosomes, which are polymers with nearly billion base pairs, are packaged in the restricted nuclear volume is not well understood. Here, the authors combine polymer physics, nonequilibrium fluctuation theorem, and simulations to quantitatively predict the force-dependent velocity and step-size distribution of condensin, which facilitates the folding of chromosomes by loop extrusion.
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