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The Journey Newsletter (November 2025)
Last month, the OHDSI community came together for the 11th annual Global Symposium to explore how we can strengthen trust in science and expand global collaboration through network studies. The event celebrated shared progress, new partnerships, and the community’s ongoing commitment to generating trustworthy, reproducible evidence around the world. Discover highlights and what’s still ahead for OHDSI in our latest newsletter. #JoinTheJourney
Podcast: Trust In Science, Building Collaboration
In the latest On The Journey podcast, Patrick Ryan and Craig Sachson look back at the recent Global Symposium, focusing first on the connections made within the community during the showcase, tutorials and workshops. They discuss the scientific content, including topics around building trust in science and global collaboration in network studies. Then they look at how OHDSI can continue building with upcoming events in Africa and Asia-Pacific. (If video does not appear, please click 'view this email in your browser.)
Community Updates
Where Have We Been?
• The 2025 Global Symposium brought together more than 400 people for a three-day event (Oct. 7-9, New Brunswick, N.J.) that included a main conference, tutorials and workgroup activities. Learn more about the event throughout this newsletter.
• Congratulations to Michael Matheny (VA, Vanderbilt) on his recent election as a new member of the National Academy of Medicine (NAM).
• Congratulations to Early-Stage Researchers Workgroup lead and recent Columbia PhD graduate Harry Reyes Nieva on being named a 2025 STAT Wunderkind, an award given to the top 30 early career scientists in North America.

Where Are We Now?
• The first-ever 2025 OHDSI Africa Symposium will be held Nov. 10-12 in Kampala, Uganda. Thank you to the symposium leadership team and the Africa Chapter for their leadership in putting together this event, which reached its maximum registration total.
• The first pan-Canadian event to bring stakeholders from across Canada who are engaged in OMOP CDM transformations and research will be held Nov. 17-18 in Toronto. The event will advance efforts to establish a Canadian OHDSI node and provide an opportunity to connect, collaborate, and gain insights into Canada’s OMOP landscape.
• The OHDSI Sweden Symposium 2025 (Nov. 5) will bring together leaders, researchers, and innovators across healthcare, life science, policy and patient organizations to explore how the international data model OMOP and assets from the open-science community OHDSI can unlock the value of Sweden’s health data.

Where Are We Going?
• The 2025 OHDSI Asia-Pacific Symposium will be held Dec. 6-7 in Shanghai, China. Registration is open, and agenda details are available on the event homepage.
• Registration is now open for the 2026 Summer School in Observational Health Data Science & Informatics, AI, and Real World Evidence, which will be held June 22-26 at the Columbia University Department of Biomedical Informatics. Now in its second-year, the Columbia OHDSI Summer School provides health professionals, researchers, and industry practitioners with an immersive, hands-on training to working with real-world health data and generating real-world evidence (RWE). Participants will explore the types of healthcare data captured during routine clinical care—such as electronic health records and administrative claims—and learn how to standardize these data using the OMOP Common Data Model to support collaborative, distributed research as part of a data network.
• The #OHDSISocialShowcase is currently highlighting research from the 2025 Europe Symposium. Please follow our LinkedInTwitter/XBluesky 
and Instagram feeds to learn more about the research happening in our community.
 
Global Collaboration and Trust In Science Take Center Stage At OHDSI 2025

More than 400 collaborators convened in New Brunswick, N.J., for the 11th OHDSI Global Symposium, where the community explored how to strengthen trust in science through large-scale, collaborative studies. Plenary talks examined topics including why network studies are essential to evidence generation, and lessons learned from decades of FDA safety review. Researchers also presented new approaches to data standards, analytics, and applications of AI, showcasing the innovation and creativity driving OHDSI’s work.

Beyond the research, the Symposium reaffirmed OHDSI’s collaborative spirit. The “State of the Community” highlighted recent milestones and global leadership, while the Collaborator Showcase allowed teams to share emerging projects that will shape the next phase of OHDSI’s journey. Posters and videos from the event are available at the symposium homepage.

The Symposium also featured a full day of tutorials, including the always-popular Introduction to OHDSI, which welcomed newcomers into the community and provided a foundation for future collaboration. Other tutorials covered methods, tools, and use cases across the research lifecycle. In addition, a day of workgroup activities allowed community members to connect within their areas of expertise, share progress, and plan initiatives that will guide OHDSI’s work in the coming year.

Event Homepage: Talks, Slides
Collaborator Showcase: Posters, Software Demos
Innovations and Collaborations Honored as OHDSI Announces 2025 Titan Award Winners

A highlight of every global symposium is the announcement of the Titan Award recipients. Annually, community members are invited to nominate individuals or institutions they feel have made significant contributions towards advancing OHDSI’s mission, vision and values. Once nominations are submitted, the OHDSI Titan Award Committee selects the award winners, who are announced and recognized during the closing of the annual global symposium.

There were more than 80 individuals and teams nominated in 2025, highlighting the wide breadth of work and collaboration that happened this past year. We were honored to present the following awards at OHDSI2025:

Data Standards: Polina Talapova
Methodological Research: Joel Swerdel
Open-Source Development: Aniek Markus, Maarten van Kessel, Jared Houghtaling
Clinical Applications: DARWIN EU Team
Community Collaboration: Liesbet Peeters, Ilse Vermeulen, Lotte Geys
Community Support: Agnes Kiragga
Community Leadership: Greg Klebanov
Titan Awards
Video: Meet the 2025 Titans
2025 'Our Journey' Report Highlights
Growing Global Community, Latest Advances
The 2025 edition of "Our Journey: Where the OHDSI community has been, and where we are going" was published prior to the Global Symposium and is available online. This annual publication provides an overview of all aspects of the OHDSI community, including its collaborators and activities, work in data, methods and open-source applications, and a list of nearly 900 peer-reviewed publications around the OMOP CDM or OHDSI tools/practices. This edition highlights the community events of 2025, testimonials from our global community, workgroups and regional teams, and plenty more.
Our Journey PDF

Dr. Andrew S. Kanter is Assistant Professor of Clinical Biomedical Informatics and Clinical Epidemiology at Columbia University and directs the Columbia International eHealth Lab (CIEL), focusing on eHealth initiatives in resource-limited settings. He is former Chief Medical Officer and is current strategic advisor at IMOHealth (IMO), where he provides strategic direction on clinical terminology and data standardization.

Dr. Kanter’s work has significantly impacted health data interoperability, particularly in low-resource environments. He led the development of the Millennium Villages Global Network (MVG-Net) for the Millennium Villages Project, an open-source information system that linked clinics across Sub-Saharan Africa. He is the Terminology and Metadata lead for the largest open source EMR project for LMICs OpenMRS, and he works closely with other open source/open science communities such as OHDSI, Open Concept Lab and OpenHIE.

Kanter discusses his career journey, why he believes work with low- and middle-income countries can impact healthcare globally, the importance of standardized vocabularies, and more in the latest collaborator spotlight.

Spotlight: Andrew Kanter
October Publications
Paradinha R, Barros V, Almeida JR, Oliveira JL. A Semantic-Driven for Cohort Data Harmonisation into OMOP CDM Schema. Stud Health Technol Inform. 2025 Oct 2;332:190-194. doi: 10.3233/SHTI251524. PMID: 41041772.

Abedian S, Yesakov E, Ostrovskiy S, Hussein R. Integrating Garmin Wearable Data into FHIR-Based Health Systems for Improved Interoperability. Stud Health Technol Inform. 2025 Oct 2;332:185-189. doi: 10.3233/SHTI251523. PMID: 41041771.

Rajwa P, Borkowetz A, Abbott T, Alberti A, Beyer K, Bjartell A, Brash JT, Chilelli A, Davies E, Meulder B, Fazekas T, Golozar A, Hijazy A, Josefsson A, Kasivisvanathan V, Kolde R, Kotik D, Leapman MS, Miszczyk M, Nicoletti R, Prinsen P, Remmers S, Ribal MJ, Rivas JG, Rodriguez-Sanchez L, Roobol MJ, Smith E, Snijder R, Steinbeisser C, Stroomberg HV, Gandaglia G, Cornford P, Evans-Axelsson S, N'Dow J, Willemse PM; PIONEER Consortium. Observational Health Data Analysis of the Cardiovascular Adverse Events of Systemic Treatment in Patients with Metastatic Hormone-sensitive Prostate Cancer: Big Data Analytics Using the PIONEER Platform. Eur Urol Focus. 2025 Oct 3:S2405-4569(25)00251-2. doi: 10.1016/j.euf.2025.08.005. Epub ahead of print. PMID: 41046191.

Badri P, Hernández I, Long J, Amin M, Friesen R. Chronic orofacial pain and psychological distress: findings from a multidisciplinary university clinic. J Oral Facial Pain Headache. 2025 Sep;39(3):152-162. doi: 10.22514/jofph.2025.057. Epub 2025 Sep 12. PMID: 41070576; PMCID: PMC12520447.

Bohn J, Gilbert JP, Knoll C, Kern DM, Ryan PB. Large-scale Empirical Identification of Candidate Comparators for Pharmacoepidemiological Studies. Drug Saf. 2025 Nov;48(11):1229-1241. doi: 10.1007/s40264-025-01569-y. Epub 2025 Jun 4. PMID: 40467833; PMCID: PMC12515211.

Lee KH, Jang S, Kim GJ, Park S, Kim D, Kwon OJ, Lee JH, Kim YH. Large Language Models for Automating Clinical Trial Criteria Conversion to Observational Medical Outcomes Partnership Common Data Model Queries: Validation and Evaluation Study. JMIR Med Inform. 2025 Oct 16;13:e71252. doi: 10.2196/71252. PMID: 41100527; PMCID: PMC12530336.

Bellas L, Català M, Burn E, Guo Y, Du M, Verhamme K, Fridgeirsson E, Duarte-Salles T, Kauko T, Kronqvist E, Brash JT, Seager S, Prieto-Alhambra D, Jödicke AM, Prats-Uribe A. Secular Trends in the Use of Valproate-Containing Medicines in Women of Childbearing Age in Europe: A Multinational DARWIN EU Network Study. Pharmacoepidemiol Drug Saf. 2025 Oct;34(10):e70232. doi: 10.1002/pds.70232. PMID: 41099219; PMCID: PMC12529455.

Razzaghi H, Dickinson K, Wieand K, Boss S, Weidlich H, Huang Y, Morse K, Mutyala SK, Nandagopal JPA, Viswanathan K, Forrest CB, Bailey LC. A multifaceted approach to advancing data quality and fitness standards in multi-institutional networks. J Am Med Inform Assoc. 2025 Oct 23:ocaf181. doi: 10.1093/jamia/ocaf181. Epub ahead of print. PMID: 41128352.

Ompad G, Cesta CE, Cohen JM, Leinonen MK, Taipale H, Li H, Guðmundsson LS, Gissler M, Sessa M. Current Use of Common Data Models in the Nordic Countries. Pharmacoepidemiol Drug Saf. 2025 Nov;34(11):e70242. doi: 10.1002/pds.70242. PMID: 41134134.

Floyd SB, Mills A, Woloff J, Lowson C, Hilton C, Oeffinger D, Hwang S. Development and validation of a computable phenotype for adolescent idiopathic scoliosis. Learn Health Syst. 2025 Jun 6;9(4):e70018. doi: 10.1002/lrh2.70018. PMID: 41169636; PMCID: PMC12569449.

Lim HC, Wong H, Philip R, Van Der Vegt A, Choo KR, Pole JD, Sullivan C. Streamlining electronic medical record data extraction and validation in digital hospitals: A systematic review to identify optimal approaches and methods. Learn Health Syst. 2025 Jul 5;9(4):e70024. doi: 10.1002/lrh2.70024. PMID: 41169627; PMCID: PMC12569454.

Jung G, Lee J, Gho SM, Han Y, Choi B, Cho JW, Kim J, Lee GH. Predicting oxcarbazepine-induced hyponatremia in adult epilepsy patients: A multicenter machine learning analysis using real-world CDM data. Seizure. 2025 Oct 16;133:167-174. doi: 10.1016/j.seizure.2025.10.004. Epub ahead of print. PMID: 41166858.

Rappoport N, Livne G, Perry Cohen N, Makover N, Eshel-Geva H, Kapach H, Hadad T, Alon Y, Rubin R, Chai S, da Villa S, Hochman O. Kineret: Israel's Largest Hospital Network Transformed into the OMOP common data model for collaborative research. PLoS One. 2025 Oct 30;20(10):e0334848. doi: 10.1371/journal.pone.0334848. PMID: 41166331; PMCID: PMC12574879.
October Presentations
Oct. 14 - Welcome To OHDSI
OHDSI Overview, How to Get Involved

Oct. 21 - Tribute to Andrew Williams
A Look at Andrew's Impact, Followed by Thoughts From Community Members

Oct. 28 - Meet The Titans
Hear from the 2025 Titan Award Winners about their Careers, 2025 Impacts
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