Current Issue | Current Research in Drug DiscoveryCurrent Issue | Current Research in Drug Discovery
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Science PublicationsenScience Publications<![CDATA[Total Synthesis of Endangered Frog Alkaloid ’Epibatidine’, A Potent Analgesic of the Future]]>
https://thescipub/abstract/crddsp.2014.26.28
Current Research in Drug Discovery, Published online: 26 January 2015; doi:10.3844/crddsp.2014.26.28’Epibatidine’ is a nicotinic alkaloid’, was first discovered in the skin of neotropical poisonous frog, ’Epipedobates tricolor’ found in Ecuador. John Daly in 1974 first isolated a trace q...]]>N.R. DhatrakM.G. Kulkarnidoi:10.3844/crddsp.2014.26.28Current Research in Drug Discovery, Published online: 2015-01-26; | doi:10.3844/crddsp.2014.26.282015-01-26Science Publications10.3844/crddsp.2014.26.28https://thescipub/abstract/crddsp.2014.26.28<![CDATA[Development and Optimization of Plant Extract Loaded Nanoemulsion Mixtures for the Treatment of Inflammatory Disorder]]>
https://thescipub/abstract/crddsp.2014.29.38
Current Research in Drug Discovery, Published online: 26 January 2015; doi:10.3844/crddsp.2014.29.38In current study, a nanoemulsion as drug delivery system (NE) of spray dried Boswellia Serrata Extract (BSE) was developed and characterized to compare it in vitro/Ex vivo diffusion with reference for...]]>Mukesh GohelTejal SoniLal HingoraniAsha PatelNayan Pateldoi:10.3844/crddsp.2014.29.38Current Research in Drug Discovery, Published online: 2015-01-26; | doi:10.3844/crddsp.2014.29.382015-01-26Science Publications10.3844/crddsp.2014.29.38https://thescipub/abstract/crddsp.2014.29.38<![CDATA[Reverse Pharmacology-A Paradigm Shift for Drug Discovery and Development]]>
https://thescipub/abstract/crddsp.2014.39.44
Current Research in Drug Discovery, Published online: 26 January 2015; doi:10.3844/crddsp.2014.39.44The current scenario of drug discovery and development is facing a model perturbation, despite significant advances in genomics, proteomics, metabolomics, combinatorial chemistry and high through put ...]]>Ashok D.B. Vaidyadoi:10.3844/crddsp.2014.39.44Current Research in Drug Discovery, Published online: 2015-01-26; | doi:10.3844/crddsp.2014.39.442015-01-26Science Publications10.3844/crddsp.2014.39.44https://thescipub/abstract/crddsp.2014.39.44<![CDATA[Design and Synthesis of Diaminotriazines as Anti-Tuberculosis DHFR Inhibitors]]>
https://thescipub/abstract/crddsp.2014.45.50
Current Research in Drug Discovery, Published online: 26 January 2015; doi:10.3844/crddsp.2014.45.50A series of novel 2,4 diamino-s-triazine was designed as potential Mycobacterium tuberculosis (Mtb) Dihydro folate reductase inhibitors. The synthesized compounds were evaluated in whole cells by empl...]]>Arundhati C LeleArchana RajuM.K. RayM.G.R. RajanMariam S Deganidoi:10.3844/crddsp.2014.45.50Current Research in Drug Discovery, Published online: 2015-01-26; | doi:10.3844/crddsp.2014.45.502015-01-26Science Publications10.3844/crddsp.2014.45.50https://thescipub/abstract/crddsp.2014.45.50<![CDATA[Determination of Optimum Values of Descriptors to Set Filters for Synthetic Tri-Pyrrole Derivatives (Prodiginines) Against Multi Drug Resistant Strain of <i>Plasmodium Falciparum</i>]]>
https://thescipub/abstract/crddsp.2014.51.59
Current Research in Drug Discovery, Published online: 26 January 2015; doi:10.3844/crddsp.2014.51.59In the present study, we have carried out extensive non-linear Quantitative-Structure Activity Relationship (QSAR) analysis to correlate in vitro anti-malarial activity against multi drug resistant st...]]>Plasmodium Falciparum]]>Vijay H. MasandDevidas T. MahajanEslam PourbasheerTaibi Ben HaddaHarsh ChauhanJ.M. GajbhiyeA. M. Alafeefydoi:10.3844/crddsp.2014.51.59Current Research in Drug Discovery, Published online: 2015-01-26; | doi:10.3844/crddsp.2014.51.592015-01-26Science Publications10.3844/crddsp.2014.51.59https://thescipub/abstract/crddsp.2014.51.59