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Metronidazole: Dosage and Indications

1. Metronidazole (brand name Flagyl) is used to treat various parasitic infections including amebiasis, giardiasis, trichomoniasis, and anaerobic bacterial infections. 2. Dosages vary depending on the indication but generally range from 250mg-1.5g daily for adults and 20-40mg/kg daily for children, administered in divided doses. 3. Common side effects include nausea, vomiting, diarrhea, and headaches while more serious reactions like neurological effects and pancreatitis have also been reported.

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ELyssa Anne Maristelle Dizon
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893 views3 pages

Metronidazole: Dosage and Indications

1. Metronidazole (brand name Flagyl) is used to treat various parasitic infections including amebiasis, giardiasis, trichomoniasis, and anaerobic bacterial infections. 2. Dosages vary depending on the indication but generally range from 250mg-1.5g daily for adults and 20-40mg/kg daily for children, administered in divided doses. 3. Common side effects include nausea, vomiting, diarrhea, and headaches while more serious reactions like neurological effects and pancreatitis have also been reported.

Uploaded by

ELyssa Anne Maristelle Dizon
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd

Generic Bran Indication Dosage Contraindicat Side Preparati Drug Nursing

Name d ion Effects on interactio responsibility


Nam and n
e Adverse
Effects
Metronidazo Flagyl Amebiasis, Tab/Susp Hypersensitivity Psychiatric Forte tab Disulfiram, Administer with
le giardiasis, Amebiasis: to imidazole disorders. 500 mg. alcohol, oral food or milk to
trichomonias Duration of Mild GI Susp 125 anticoagula minimize GI
is. Non- treatment: 7 disturbances mg/5 mL x nts, lithium, irritation.
specific consecutive days . Urticaria, 60 mL. cyclosporin,
vaginitis. Adult: 1.5g daily in flushing, Supp 1 g. phenytoin Tablets may be
Treatment of 3 divided doses. pruritus, IV infusion or crushed for
anaerobic Pedia 30-40 glossitis with 500 Phenobarbit patients with
infections. mg/kg/day in 3 dryness of mg/100mL. al, 5- difficulty
Prophylaxis divided doses. mouth. flourouracil. swallowing.
of post- Convulsion,
operative Giardiasis: headache, Instruct patient
infections. Adult 0.75-1 g dizziness, to take
Intestinal daily. leukopenia, medication
and hepatic Pedia 10-15 yrs: peripheral exactly as
amebiasis. 500 mg/day, 5-10 sensory directed evenly
yrs: 375 mg/day, 2- neuropathy. spaced times
5 yrs: 250 mg/day. Pancreatitis. between dose,
Reddish or even if feeling
Trichomoniasis: brown urine. better
Women/Men:
Single dose of 2 g Do not skip
or 500 mg/day in 2 doses or double
divided doses for up on missed
10 days. doses. If dose is
missed, take as
Treatment of soon as
anaerobic remembered if
infections: not almost time
Adult: 1-1.5g/day for next dose.
Pedia: 20-30
mg/kg/day. If for compelling
Supp Adult: 1 supp reasons,
TID for 7 days. metronidazole
Pedia: 15mg/kg must be
BW/dose TID for 7 administered
days. longer than the
usually
IV Curative recommended
treatment of duration, it is
anaerobic recommended
infections: that
Adult: 1-1.5 g/day hematological
as 2 or 3 IV tests, especially
infusion. leucocyte count
Pedia: 20-30 should be
mg/kg/day as 2 or carried out
3 IV infusions.

Prophylaxis of post-
operative
infections:
Adult: Slow IV
infusion (30-60
mins) of 500 mg
before surgery and
2 IV infusions of
500 mg 8 and 16
hours later.
Pedia: Same
protocol at the
dose of 20-30
mg/kg/day.

Intestinal and
hepatic amebiasis:
Adult: 1.5g/day.
Pedia: 30-40
mg/day IV
infusions.

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