Scribd
Upload
461 views2 pages

Sodium Thiosulphate Standardization Guide

This document provides the procedure for preparing and standardizing a 0.1M sodium thiosulfate solution. It details the purpose, instrumentation, reagents, and step-by-step procedure for preparation by dissolving sodium thiosulfate and sodium carbonate in water, and for standardization by titrating the solution against a standard potassium bromate solution with starch indicator. The calculation for determining the molarity of the sodium thiosulfate solution based on the titration results is also included.

Uploaded by

Mubarak Patel
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
461 views2 pages

Sodium Thiosulphate Standardization Guide

This document provides the procedure for preparing and standardizing a 0.1M sodium thiosulfate solution. It details the purpose, instrumentation, reagents, and step-by-step procedure for preparation by dissolving sodium thiosulfate and sodium carbonate in water, and for standardization by titrating the solution against a standard potassium bromate solution with starch indicator. The calculation for determining the molarity of the sodium thiosulfate solution based on the titration results is also included.

Uploaded by

Mubarak Patel
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.

RENE INDUSTRIES LIMITED

GENERAL TEST PROCEDURE

TITLE: PREPARATION AND STANDARDIZATION OF 0.1 M SODIUM THIOSULPHATE SOLUTION

GTP NUMBER SUPERSDES Effective Date Review Date Page No.


GTP001-00 Nil. 11/2011 10/2013 Page 1 of 2

1.0 PURPOSE
1.1 To lay down the procedure for Preparation and Standardization of 0.1M Sodium Thiosulphate
Solution.

2.0 INSTRUMENTATION & APPARATUS


2.1 Burette
2.2 Pipette
2.3 Iodine flask
2.4 1000ml volumetric flask
2.5 250 ml volumetric Flask

3.0 REAGENTS
3.1 Sodium Thiosulphate AR grade
3.2 Sodium carbonate AR grade
3.3 Potassium bromate AR grade
3.4 Potassium iodide AR grade
3.5 2M hydrochloric acid
3.6 Starch solution

4.0 PROCEDURE
4.1 Preparation:
4.1.1 Dissolve 25.0 g of sodium Thiosulphate and 0.2 grams of Sodium carbonate in Carbon dioxide
free water and dilute to 1000 ml with the same solvent.
4.2 Standardization:
4.2.1 Weigh accurately about 0.2 gram of Potassium bromate previously dried to constant weight at
180°C, in sufficient water to produce 250 ml.
4.2.2 To 50ml of this solution add 2 grams of Potassium iodide and 3 ml of 2M hydrochloric acid
and titrate with the 0.1M sodium thiosulphate solution using starch solution, added towards the
end of the titration as indicator until the blue colour is discharged.

PREPARED BY CHECKED BY APPROVED BY AUTHORISED BY


NAME SWARNA OKOT FRANCIS ANJI REDDY. G MWIGO. J.B
DESIGNATION Q.C- CHEMIST Q.C- MANAGER Q.A- MANAGER PHARMACIST-IN-CHARGE.
SIGNATURE
DATE
QAP006/F06-00
RENE INDUSTRIES LIMITED

GENERAL TEST PROCEDURE

TITLE: PREPARATION AND STANDARDIZATION OF 0.1 M SODIUM THIOSULPHATE SOLUTION

GTP NUMBER SUPERSDES Effective Date Review Date Page No.


GTP001-00 Nil. 11/2011 10/2013 Page 2 of 2

4.2.3 Each ml of 0. 1M Sodium Thiosulphate = 0.002784 g of Potassium bromate.

4.2.4 Calculation

Sample weight x 50 x 0.1


= -----------------------------------------
Titre volume x 250 x 0.002784

# Store in bottles with well - fitted stoppers.


# Use within 30 days from the date of preparation.

5.0 REFERENCES
5.1 I.P 1996 Page No –A213

END OF DOCUMENT

PREPARED BY CHECKED BY APPROVED BY AUTHORISED BY


NAME SWARNA OKOT FRANCIS ANJI REDDY. G MWIGO. J.B
DESIGNATION Q.C- CHEMIST Q.C- MANAGER Q.A- MANAGER PHARMACIST-IN-CHARGE.
SIGNATURE
DATE
QAP006/F06-00

You might also like