LESSON 4: DOSAGE AND CALCULATIONS
Obongen, Aila Marie G. I BSN2I-1
CHECK-IN ACTIVITY:
PRACTICE PROBLEMS. Show your solutions
1. Order: Ceftriaxone 1.5 g IM now
Available: Ceftriaxone 2 g. vial
a. How many milliliters of diluent is need for reconstitution?
As the ordered dose is given in the form of IM injection, 4.2 ml of 1% lidocaine Hydrochloride
Injection or sterile water for injection are used as the diluent for reconstitution. After
reconstitution, 350 mg would be present in one ml of the solution.
As per the instruction, 4.2 ml of the diluent is required to reconstitute the vial.
b. How many milliliters will the nurse administer for the now dose?
Given:
• Dose on hand (H): 350 mg / 1 ml
• Ordered dose (D): 1.5 g or 1500 mg
• Quantity of dose (Q): 1
Solution:
D / H x Q = Desired dose
[{1.5 g x 1000 mg} / 350 mg] x 1
[1500 mg / 350 mg] x 1 = 4.28 ml
4.28 ml of 350mg/ml of the ceftriaxone must be administered to the patient to get the
prescribed dose of 1.5 g or 1500 mg.
2. Order: 1000 mL of D5 NSS to infuse over 12 hours.
Available: Microdrip set with a drop factor of 60 gtt / mL
a. Calculate the IV flow rate in drops per minute.
Given:
• Volume: 1000 mL
• Time: 12 hrs.
• Drop factor: 60 gtt / mL
Solution:
[Total IV volume /time (minute)] x drop factor = drops per minute
[1000 mL / {12 hrs. x 60}] x 60
[1,000 / 720 mins.] x 60
1.39 x 60 = 83 gtt / mL