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Python (Bioinformatics)

47 repositories
Python 10 2 Updated Dec 7, 2023

Tool for the detection and quantification of alternative splicing events from RNA-Seq data.

Python 111 35 Updated Apr 13, 2026

A Python implementation of the DESeq2 pipeline for bulk RNA-seq DEA.

Python 746 82 Updated Apr 14, 2026

Toolkit to run Python benchmarks

Python 925 96 Updated Mar 21, 2026

pyranges/bioframe for polars

Python 18 Updated Jul 20, 2023

Pyranges: a Python framework for ultrafast sequence interval operations

Python 52 8 Updated Apr 16, 2026

Making Snakemake workflows into full-fledged command line tools since 1999.

Python 51 1 Updated Apr 19, 2018

Annotated data.

Python 732 189 Updated Apr 16, 2026

GFF and GTF file manipulation and interconversion

Python 316 80 Updated Mar 31, 2026

Efficiently read and write sequencing data from Python

Python 70 9 Updated Oct 12, 2025

Package for fetching metadata and downloading data from SRA/ENA/GEO

Python 354 63 Updated Dec 9, 2025

Quality of life improvements for Bioinformatics in Python.

Python 32 4 Updated Apr 16, 2026
Jupyter Notebook 21 1 Updated Feb 1, 2026

deploy a snakemake pipeline directly from version control (under development)

Python 25 13 Updated Mar 12, 2026

Incubator for useful bioinformatics code, primarily in Python and R

Python 643 243 Updated Feb 5, 2025

A high-performance BigWig and BigBed library in Rust

Rust 113 8 Updated Feb 13, 2026

Oxbow makes genomic data ready for high-performance analytics.

Rust 153 15 Updated Mar 21, 2026

This is the development home of the workflow management system Snakemake. For general information, see

Python 2,754 633 Updated Apr 16, 2026

Performant Pythonic GenomicRanges

Python 494 50 Updated Jan 27, 2026

A Snakemake workflow and MrBiomics module for performing genomic region set and gene set enrichment analyses using LOLA, GREAT, GSEApy, pycisTarget and RcisTarget.

Python 75 4 Updated Apr 16, 2026

scikit-bio: a community-driven Python library for bioinformatics, providing versatile data structures, algorithms and educational resources.

Python 1,189 326 Updated Apr 15, 2026

Python library for array programming on biological datasets. Documentation available at: https://bionumpy.github.io/bionumpy/

Python 290 17 Updated Jun 16, 2025

Genomic interval operations on Pandas DataFrames

Python 191 35 Updated Apr 6, 2026

Declarative creation of composable visualization for Python (Complex heatmap, Upset plot, Oncoprint and more~)

Python 309 12 Updated Feb 3, 2026

Simplifies parallel processing of DNA sequencing reads

Python 9 2 Updated Feb 3, 2026

Biological sequence analysis for the modern age.

Python 271 29 Updated Feb 22, 2026

Container class to represent genomic locations and support genomic analysis

Python 27 4 Updated Apr 13, 2026

Work with bioinformatic files using Arrow, Polars, and/or DuckDB

Rust 196 13 Updated Mar 10, 2025

Feature-rich Python implementation of the tximport package for gene count estimation.

Python 44 2 Updated Apr 14, 2026

Snakemake workflow management system and CLI generation tool

Python 66 3 Updated Oct 22, 2025