UNL Research Annual Report 2005-2006
UNL Research Annual Report 2005-2006
“When you focus the laser to its highest intensity, you are creating
conditions that have never been produced on earth.”
Donald Umstadter
Zeng’s team was the first to combine quantum chemistry Grants from the U.S. Department of Energy, the National
calculations with a powerful computerized search technique Science Foundation-funded Materials Research Science and
to identify previously unknown nanoscale structures and Engineering Center at UNL and the Nebraska Research
substances. With the help of UNL’s PrairieFire super- Initiative support this research.
“We were shocked when we first saw these. No one expected the cage structure.”
Xiao Cheng Zeng
Above: Xiao Cheng Zeng (right) and graduate research assistant Satya Bulusu.
Opposite: An illustration shows a hollow nanocage made of 17 gold atoms.
6 PHYSICAL SCIENCES & ENGINEERING 7
Pressing the film against a surface pushes the nanoparticles Existing sensing devices are low-resolution, expensive and rigid, The sensor also could be used to give robots a more
together, creating changes in electrical current and light making them unsuitable for surgical applications. The UNL humanlike sense of touch, which would be a major stride
emissions that a digital camera can capture. For example, sensor should be significantly cheaper and offers resolution on in enhancing robots’ capability to perform delicate tasks.
when the sensor is pressed against a penny, it detects par with a human finger. It also can be made to cover an area
creases in Abraham Lincoln’s clothing. of one square meter or larger and can cover complex shapes. The National Science Foundation and Office of Naval
Research support this research.
10 PHYSICAL SCIENCES & ENGINEERING 11
Scientists believe that mitochondria, cellular Bacteria perform that function using
structures vital to humans, animals and an entirely different protein so scientists
many other organisms, evolved when one know the function evolved separately
type of single-celled organism merged into in archaea and bacteria. Both proteins
another. The exact nature of that evolutionary process also are found in human cells, one in the cytoplasm and
remains unknown. Powers and colleagues from several the other in the mitochondria, providing valuable clues
universities found a link between these two distinct to their origins and our understanding of early evolution.
organisms — and to humans. The discovery was featured on the cover of the November
To infect a plant, Pseudomonas syringae and similar 2005 issue of Protein Science.
pathogens inject up to 30 proteins using a microscopic Using nuclear magnetic resonance, Powers and colleagues
syringe-like process called a Type III protein injection system. determined the 3-D structure of AF2095, a protein found in Nebraska Tobacco Settlement Biomedical Research
an archaea, a class of single-cell organisms that thrives in funds, the National Institutes of Health, National
relatively high temperatures. Scientists hoped the structure Science Foundation and U.S. Department of Energy
would provide clues to its function. They found AF2095’s helped fund this work.
James Alfano
16 LIFE SCIENCES 17
ORGANIC FARMING
RESEARCH EXPANDING
PLANT TRANSFORMATION LAB IS BIOTECH PIPELINE Organic farming is among the fastest growing segments
of U.S. agriculture. A new initiative is expanding UNL’s
organic farming research and education efforts to help
growers make the most of this expanding market.
Identifying potentially useful genes is just the first step
toward creating enhanced plants for the real world. A With funding from a four-year $750,000 grant from
unique research resource at UNL simplifies and speeds USDA’s Cooperative State Research, Education and
the often complex journey from discovery in the lab to Extension Service, scientists in the university’s Institute
the field and potential commercialization for promising of Agriculture and Natural Resources are laying the
genetically modified plants. foundation for long-term organic farming research. Goals
include establishing UNL’s first certified organic research
The Plant Transformation Core Research Facility offers a fields, launching focused crop production research,
complete “agricultural biotechnology pipeline,” said plant working closely with the state’s organic farmers and
scientist Tom Clemente, facility manager. It’s a one-stop incorporating organic farming concepts into UNL’s
shop for researchers and companies seeking to genetically research, teaching and extension missions.
engineer plants with
improved or specialized Establishing 20- to 40-acre certified research plots at four
characteristics, such as university research farms across the state is a key component.
drought or insect resist- Certification takes three years. Devoting land to organic
ance, or for scientists research around the state means each site can focus on
probing a specific plant locally important production issues while the network
gene’s role. Tiny genetically enhanced plants in growth medium. will provide statewide results, said Charles Shapiro, a soil
scientist at the Northeast Research and Extension Center
Clemente’s team is and one of seven project co-leaders.
known for its expertise As the only university with all of the components The processing facility – the latest addition to UNL’s
in successfully inserting to develop, field test and process genetically resources – completes the research pipeline. It allows A UNL Extension educator is coordinating the project and
or altering plant genes. engineered plants and products on such a researchers to develop and test new products from planning how to share findings and organic concepts
While most facilities large scale, UNL offers an indispensable genetically enhanced plants. For example, Clemente and with farmers and students. Organic growers are advising
specialize in transforming resource for researchers and companies a colleague are processing and testing oil from a soybean on the project and researchers are conducting studies on
a few plants, UNL’s lab nationwide, Clemente said. they developed especially for biodiesel production. cooperating certified organic farms. The new infrastructure
can genetically alter will create opportunities for broader organic farming
any important Midwest For example, when Monsanto Co. launches a new The Nebraska Research Initiative, Nebraska Soybean Board, research at UNL.
crop plant and several Lab manager Shirley Sato (foreground) and herbicide-resistant soybean in a few years, it will North Central Soybean Board and United Soybean Board
Kwang-Hoon Oh in UNL’s Plant Transformation
plants used extensively Core Research Facility. in part be thanks to the facility’s capabilities. are among the organizations funding projects in the facility.
for research. The team UNL biochemist Don Weeks discovered a gene The team also is training plant breeders to maintain
doesn’t stop with successfully inserting the gene. that helps soybeans and other broadleaf crops withstand regulated, genetically engineered plants in the field through
spraying with dicamba, a widely used broadleaf herbicide. a $600,000 USDA grant.
Researchers literally take genetically modified plants from Clemente’s team successfully inserted the gene in soybean
the lab to the processing plant. They grow and test plants DNA, then tested the soybeans in the greenhouse and the
in the greenhouse and later in plots dedicated to field field. This process would have taken far longer without the
testing transgenic plants before processing a harvested facility. UNL patented Weeks’ discoveries, which Monsanto
crop to ensure it delivers desired qualities or components. is developing under a university licensing agreement.
18 LIFE SCIENCES 19
Expanding Partnerships
with Zambia, China
The Fogarty International Training Programs
provide a base from which UNL is launching
additional collaborations with the University
of Zambia and Nankai University in China.
Architecture student designs for New Orleans. “The publication documents not only the Sheldon’s
Designing for New Orleans collection but also the uniqueness of the history of the
collection,” said Karen O. Janovy, Sheldon’s education Karen Janovy
After Hurricane Katrina devastated the Gulf Coast, public and commercial buildings and multifamily housing, curator and the book’s editor. “The contributing essayists are
UNL Architecture Dean Wayne Drummond got a call for which they compiled into a master plan for the area. all experts within the field of 20th-century art. Publishing this
help from his friend Cliff James, director of the Urban Potter’s students designed single-family housing prototypes type of scholarship is an important mission of the museum.”
Design Research Center in New Orleans. That call set in that matched New Orleans’ culture and environment.
motion a whirlwind of research and design for Drummond, The project, conceived of as a companion piece to a 1988
architecture professor Jim Potter and 27 students. “This isn’t just a class project, it’s an amazing lesson in the publication on the Sheldon’s painting collection, was funded
sociology of our country,” Drummond said. A book and CD by the National Endowment for the Arts, Nebraska Art
Students in Drummond’s design studio course toured New containing the plan provides a reference for agencies and Association, Cooper Foundation, Elizabeth Firestone Graham
Orleans, assessing the extensively damaged Jubilee City decision makers working to rebuild the city. Foundation, Institute of Museum and Library Services, Paul
neighborhood near the Superdome. Students designed Klein Art Works, Henry Luce Foundation and University
of Nebraska Foundation.
GENES AND POLITICAL TEMPERAMENT exploring its potential as a dietary supplement. “I’m
excited about the potential of this for consumers looking
to manage their cholesterol,” Carr said.
Political scientist John Hibbing assumed, like most of us, to explore how genetics affects our beliefs of how society
that our political views stem from our life experiences. So should be organized – our political temperament. He and his
he was “shocked” by his own findings and so were others. colleagues are expanding this research to explore specific Better Bone Implants
It seems our conservative or progressive outlooks have as genes that may influence political behavior.
much to do with our genes as our upbringing. Chemist Jody Redepenning is building better bones – or,
However, Hibbing stresses that doesn’t mean there’s a to be more precise, better implants.
Hibbing, a UNL Foundation Regents University Professor of specific gene that makes one liberal, conservative or
Political Science, along with John Alford of Rice University even apolitical. Rather, genes create a propensity to view Redepenning discovered a simple electrochemical process
and Carolyn Funk of Virginia Commonwealth University, the world in certain ways and that viewpoint influences for making bone implants. UNL patented his process,
studied attitudes of more than 8,000 sets of twins about 28 our political decisions. For example, characterizing a which could lead to a biocomposite material that could be
issues, such as capital punishment and taxes. By subtracting guest-worker program as “amnesty” for illegal immigrants used to make bone replacements, screws, other orthopedic
the rate at which fraternal twins, who share half of their may stem from an underlying belief that perceived appliances or medical devices. This biocomposite is as
genes, agreed on an issue from the rate that genetically rule-breakers should be punished. strong and flexible as bone and has applications in
identical twins agreed, researchers calculated how much dentistry as well as orthopedics.
genetics influenced attitudes on that issue. They assumed So, are bloggers and talk show hosts discoursing for nothing?
twins raised together experienced similar upbringings. Perhaps, but not because we’re genetically inconvincible. During the healing process, the body ultimately would
absorb the material and redeposit it as living bone.
Overall, they found 53 percent of political beliefs come “Nobody’s talking genetic determinism,” says Hibbing, “The idea is for it to go away,” he said.
from genetic inheritance, though the percentage varied adding that people’s politics are a complicated mix of
somewhat depending on the issue. Opinions on school numerous genes interacting with the environment. No Tim Carr with cholesterol-fighting compound. Redepenning is refining the process for producing the
prayer, property taxes and the draft, for example, were one should fear a day when genetic engineering could biocomposite. He thinks scientists eventually could
most strongly influenced by genes, while views on manipulate elections. revealed stearic acid, a “good” saturated fat, also fights come up with something stronger than bone.
federal housing and divorce were less so. cholesterol. The combination outperformed plant sterol
Instead, Hibbing hopes his research leads to greater food additives in animal studies and appeared to work
Scientists have long known genes play a role in our personal understanding. Your cousin may not be willfully bullheaded; as well as widely prescribed cholesterol-lowering statin
and social temperaments, but Hibbing is one of the first he’s just genetically wired to view the world differently. drugs. Now it’s being tested on people.
28 EDUCATION & OUTREACH 29
GOLDWATER RECIPIENTS
UNDERGRADS EXPERIENCE RESEARCH FIRST HAND Research is an essential part of the college learning experience
for UNL’s two 2006-07 Goldwater Scholarship recipients.
The National Science Foundation’s Research Experience
for Undergraduates (REU) program attracts students from
Jeanine Frey, a biochemistry major from Hay Springs, and
smaller, less research-oriented colleges and historically
James McFarland, an electrical engineering major from
minority institutions, to UNL. One goal is to encourage
Lincoln, are among 323 students nationwide to receive this
minority students to consider graduate school at UNL or
scholarship based on academic merit. Chemistry major
elsewhere as part of a broader effort to enhance diversity
Jessica Peinado earned an honorable mention. Named
in the professions and sciences.
for the late Arizona Sen. Barry Goldwater, the nationally
competitive scholarship encourages careers in math,
the natural sciences and engineering. It’s the premier
Redox Biology undergraduate award of its type in these fields.
The museum’s extensive collection of fossils from mammals UNL’s Native American Career Ladder has graduated
that lived in North America over the past 40 million years 19 Native American students, including four in 2006,
ranks among the nation’s top 10 most significant. A two-year, who are teaching mostly in reservation schools at
$498,000 grant from the National Science Foundation is Macy, Santee, Walthill and Winnebago. Most were
funding facility renovations, reorganization and creation the first in their family to receive a bachelor’s degree,
of an online database. said Nancy Engen-Wedin, of the College of Education
and Human Sciences and project director. “We now
Leading this work are Robert Hunt Jr. and Michael Voorhies, have more certified Native American teachers in
professors of geosciences and museum curators in UNL’s Nebraska than we’ve had in our state’s history.”
nationally recognized vertebrate paleontology research
program. They will develop the database featuring much The project began in 1999 with a $1.25 million
of the collection and centralize the fossils, which now reside six-year U.S. Department of Education grant. In
in several locations. This work will make information about 2006, UNL received a second four-year $750,000
the collection easily available on the Web for scientists and education department grant to extend this effort
educators worldwide. with the Indigenous Roots Teacher Education
Program. The new program, which has enrolled 15
“This will give us access students, continues a partnership between UNL, Little
to specimens of very rare Priest Tribal College, the Nebraska Department of
and unusual prehistoric Education and five northeast Nebraska K-12 schools.
animals that in some
cases have been in plaster
jackets for many years,” TRAINING NATIVE AMERICAN TEACHERS
Voorhies said. “It’s almost
like opening Christmas Students must have associate degrees to enter the program.
presents from 50, 60, 70 They graduate from UNL after taking distance and traditional
years ago that haven’t classes at Little Priest, Nebraska Indian Community College
been accessible to the and UNL. Coursework emphasizes Native language learning
Nancy Engen-Wedin
scientific community.” and culturally relevant approaches.
The museum’s fossils were Research suggests Native students benefit academically Bill Lopez heads the five-year $1.97 million U.S.
last cataloged nearly from having Native American teachers. “It will make a Department of Education grant that includes educators
15 years ago. Strides in significant difference if we continue to place Native role and students from UNL, Northeast Community College
database and Web tech- models as teachers in classrooms with Native American in Norfolk, Central Community College-Columbus and
nology will make this new kids,” Engen-Wedin said. Wayne State College. The first 10 students received
effort more user-friendly their associate degrees in 2005 and transferred to
and comprehensive. The College of Education and Human Sciences and UNL UNL’s elementary education program. Students take
Extension are working on a similar project for English courses from UNL and Wayne State. The first group
language learners. The Northeast Nebraska Para will graduate in December 2007.
Educator Career Ladder project aims to place bilingual
Collections manager George
Corner and some of the fossils minority teachers in northeast Nebraska’s diverse
that will be available online. classrooms. The project is developing a cadre of ethnically
and linguistically diverse elementary teachers.
34 EXTENDING OUR REACH 35
FINANCIALS CREDITS
The 2005-2006 Annual Report is published by the University of
Research Funding by Federal Agency Nebraska–Lincoln Office of Research and Graduate Studies. More
information is available at [Link]/research or contact:
35% Department of Health & Human Services National Science Foundation 20%
(including NIH) Prem S. Paul
Vice Chancellor for Research and Dean of Graduate Studies
302 Canfield Administration Building
University of Nebraska–Lincoln
Lincoln, Nebraska 68588-0433
(402) 472-3123
U.S. Department of Agriculture 20%
ppaul2@[Link]
Writer/Editors:
2% Other
Vicki Miller, research communications coordinator
1% NASA
1% Department of Interior Monica Norby, assistant vice chancellor for research
1% Environmental Protection Agency Department of Defense 11%
2% Department of Transportation Contributing Writer/Editors:
3% Department of Education Kim Hachiya, Gillian Klucas, Nathan Meier, Daniel R. Moser,
4% Department of Energy Tisha Gilreath Mullen, Sara Pipher, Tom Simons
$157.8
90 150
$91.6
$151.4
$145.8
$84.6
80 140
$142.6
$74.4
70 130
FY02 FY03 FY04 FY05 FY06 FY02 FY03 FY04 FY05 FY06