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Cefuroxime (Zegen) Antibiotic Overview

The document summarizes information on two drug studies. For Cefuroxime, it indicates the generic and brand names, classification, dosage, frequency, route of administration, indications for use including various infections, contraindications of known cephalosporin allergies, and potential side effects. For Amikacin, it provides the brand name, classification, dosage, frequency, route and indications for treating severe bacterial infections, contraindications including certain medications, and nursing considerations about hydration, monitoring, and storage.

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Jazel Opinion
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397 views3 pages

Cefuroxime (Zegen) Antibiotic Overview

The document summarizes information on two drug studies. For Cefuroxime, it indicates the generic and brand names, classification, dosage, frequency, route of administration, indications for use including various infections, contraindications of known cephalosporin allergies, and potential side effects. For Amikacin, it provides the brand name, classification, dosage, frequency, route and indications for treating severe bacterial infections, contraindications including certain medications, and nursing considerations about hydration, monitoring, and storage.

Uploaded by

Jazel Opinion
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOC, PDF, TXT or read online on Scribd

DRUG STUDY Indication/ Contraindication Generic Name: Cefuroxime Brand Name: Zegen Classification: Antibiotics Dosage: 93mg Frequency:

Q12h Route: IV Drip Date Ordered: January 12, 2011 Indication: Treatment of bone and joint infections, bronchitis (and other lower respiratory tract infections), gonorrhea, meningitis, otitis media, peritonitis, pharyngitis, sinusitis, skin infections, surgical infections and UTI. Contraindication: Known allergy to cephalosporins Mechanism of Action Bind to bacterial cell wall membrane which causes cell death. Side Effects/ Adverse Effects Thrombophlebitis, Pruritus, urticaria, positive Coombss test, diarrhea, nausea, pseudomembrenous colitis,. Decrease in Hb and hematocrit, transient increase in liver enzymes, elevation in serum creatinine and BUN possible, seizure and angioedema Nursing Considerations

Before initiating therapy, obtain a history to determine previous use of and reaction to penicillin or cephalosporins. Person with a negative history of penicillin sensitivity may still have an allergic response. Obtain specimens for culture and sensitivity before initiating the therapy. Observe patient for signs and symptoms of anaphylaxis Assess patient for renal dysfunction and adjust accordingly.

Indication/ Contraindication Generic Name: Amikacin Brand Name: Amikin Classification: Antibiotics Dosage: 28mg Frequency: Once daily Route: IV Drip Date Ordered: January 12, 2011

Mechanism of Action

Side Effects/ Adverse Effects allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue difficulty breathing hearing loss, ringing in the ears dizziness, loss of balance fever less urine low blood pressure numbness, tingling tremor unusually weak or tired

Nursing Considerations

Indication: Amikacin is used to treat Amikacin is an severe or serious antibiotic. It fights bacterial infections. bacteria in the body. Amikacin is used to treat severe or serious bacterial infections. Contraindication: Do not take this medicine with any of the following medications: cidofovir This medicine may also interact with the following medications: amphotericin B, bacitracin, cisplatin, colistin, diuretics like ethacrynic acid or furosemide, other antibiotics

Adequate hydration is important during treatment with amikacin. It is important that the medication be given on a regular schedule and for the entire amount of time prescribed by your doctor. Amikacin may cause damage to the kidneys and/or nerves. Kidney function and drug levels in the blood may be monitored with blood tests during treatment. Your healthcare provider will store amikacin as directed by the manufacturer or give you detailed storage instructions if you are storing the medication at home.

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